Publications -- Center for Biologic Imaging

Collins JL, Vodovotz Y, Hierholzer C, Villavicencio RT, Liu S, Alber S,Gallo D, Stolz DB, Watkins SC, Godfrey A, Gooding W, Kelly E, Peitzman AB,Billiar TR. Characterization of the expression of inducible nitric oxide synthase in rat and human liver during hemorrhagic shock. Shock. 2003 Feb;19(2):117-22.(COVER)

Feili-Hariri M, Falkner DH, Gambotto A, Papworth GD, Watkins SC, Robbins PD,Morel PA. Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis. Hum Gene Ther. 2003 Jan 1;14(1):13-23

Seidberg NA, Clark RS, Zhang X, Lai Y, Chen M, Graham SH, Kochanek PM, Watkins SC, Marion DW. Alterations in inducible 72-kDa heat shock protein and the chaperone cofactor BAG-1 in human brain after head injury. J Neurochem. 2003 Feb;84(3):514-21.

Bertera S, Crawford ML, Alexander AM, Papworth GD, Watkins SC, Robbins PD, Trucco M. Gene Transfer of Manganese Superoxide Dismutase Extends Islet Graft Function in a Mouse Model of Autoimmune Diabetes. Diabetes. 2003 Feb;52(2):387-393.

Pezzone MA, Watkins SC, Alber SM, King WE, De Groat WC, Chancellor MB,Fraser MO. Identification of c-kit-Positive Cells in the Mouse Ureter: The Interstitial Cells of Cajal of the Urinary Tract.Am J Physiol Renal Physiol. 2003 Jan 21

Ganta SR, Piesco NP, Long P, Gassner R, Motta LF, Papworth GD, Stolz DB, Watkins SC, Agarwal S. Vascularization and tissue infiltration of a biodegradable polyurethane matrix. J Biomed Mater Res. 2003 Feb 1;64A(2):242-248.

Sullivan ML, Youker RT, Watkins SC, Brodsky JL. Localization of the BiP Molecular Chaperone with Respect to Endoplasmic Reticulum Foci Containing the Cystic Fibrosis Transmembrane Conductance Regulator in Yeast. J Histochem Cytochem. 2003 Apr;51(4):545-8.

Leong PL, Andrews GA, Johnson DE, Dyer KF, Xi S, Mai JC, Robbins PD, Gadiparthi S, Burke NA, Watkins SC, Rubin Grandis J. Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth. Proc Natl Acad Sci U S A. 2003 Mar 14

Du L, Zhang X, Han YY, Burke NA, Kochanek PM, Watkins SC, Graham SH, Carcillo JA, Szabo C, Clark RS. Intra-mitochondrial poly-ADP-ribosylation contributes to NAD+ depletion and cell death induced by oxidative stress. J Biol Chem. 2003 Mar 7 ( COVER)

Geng X, Li L, Watkins S, Robbins PD, Drain P. The Insulin Secretory Granule Is the Major Site of K(ATP) Channels of the Endocrine Pancreas. Diabetes. 2003 Mar;52(3):767-76.

Redlinger RE Jr, Shimizu T, Remy T, Alber S, Watkins SC, Barksdale EM Jr. Cellular mechanisms of interleukin-12-mediated neuroblastoma regression. J Pediatr Surg. 2003 Feb;38(2):199-204.

Nadler EP, Go LL, Beer-Stolz D, Watkins SC, Schall LC, Boyle P, Ford HR. Transcellular Transport Is not Required for Transmucosal Bacterial Passage across the Intestinal Membrane Ex Vivo. Surg Infect (Larchmt). 2003 Winter;1(4):265-72.

Harshyne LA, Zimmer MI, Watkins SC, Barratt-Boyes SM. A role for class a scavenger receptor in dendritic cell nibbling from live cells. J Immunol. 2003 Mar 1;170(5):2302-9

Yuan X, Ma Z, Zhou W, Niidome T, Alber S, Huang L, Watkins S, Li S. Lipid-mediated delivery of peptide nucleic acids to pulmonary endothelium. Biochem Biophys Res Commun. 2003 Feb 28;302(1):6- 11.

Zhang J, Wilson A, Alber S, Ma Z, Tang ZL, Satoh E, Mazda O, Watkins S,Huang L, Pitt B, Li S. Prolonged gene expression in mouse lung endothelial cells following transfection with Epstein-Barr virus-based episomal plasmid. Gene Ther. 2003 May;10(9):822-6.

Morse D, Otterbein LE, Watkins S, Alber S, Zhou Z, Flavell RA, Davis RJ,Choi AM. Deficiency in the c-Jun-NH2-terminal kinase (JNK) signaling pathway confers susceptibility to hyperoxic lung injury in mice. Am J Physiol Lung Cell Mol Physiol. 2003 Mar 21

Sullivan ML, Youker RT, Watkins SC, Brodsky JL. Localization of the BiP Molecular Chaperone with Respect to Endoplasmic Reticulum Foci Containing the Cystic Fibrosis Transmembrane Conductance Regulator in Yeast.J Histochem Cytochem. 2003 Apr;51(4):545-8.

Ray P, Devaux Y, Stolz DB, Yarlagadda M, Watkins SC, Lu Y, Chen L, Yang XF, Ray A. Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia. Proc Natl Acad Sci May 13;100(10):6098-103

Yang Q, Hokland ME, Bryant JL, Zhang Y, Nannmark U, Watkins SC, Goldfarb RH, Herberman RB, Basse PH. Tumor-localization by adoptively transferred, interleukin-2-activated NK cells leads to destruction of well-established lung metastases.Int J Cancer. 2003 Jul 1;105(4):512-9.

Thomas SM, Zeng Q, Dyer KF, Suscovich TJ, Kanter PM, Whalen JD, Watkins SF,Rubin Grandis J. Tissue distribution of liposome-mediated epidermal growth factor receptor antisense gene therapy. Cancer Gene Ther. 2003 Jul;10(7):518-528.

Wang ZZ, Washabaugh CH, Yao Y, Wang JM, Zhang L, Ontell MP, Watkins SC, Rudnicki MA, Ontell M. Aberrant development of motor axons and neuromuscular synapses in MyoD-null mice.J Neurosci. 2003 Jun 15;23(12):5161-9.

Song R, Kubo M, Morse D, Zhou Z, Zhang X, Dauber JH, Fabisiak J, Alber SM, Watkins SC, Zuckerbraun BS, Otterbein LE, Ning W, Oury TD, Lee PJ, McCurry KR,Choi AM. Carbon Monoxide Induces Cytoprotection in Rat Orthotopic Lung Transplantation via Anti-Inflammatory and Anti-Apoptotic Effects.Am J Pathol. 2003 Jul;163(1):231-42.

Chi X, Anselmi K, Watkins S, Gandhi CR. Prevention of cultured rat stellate cell transformation and endothelin-B receptor upregulation by retinoic acid. Br J Pharmacol. 2003 Jun;139(4):765-774.

Chen CH, Seguin-Devaux C, Burke NA, Oriss TB, Watkins SC, Clipstone N, Ray A. Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx,and NFATc translocation causing inhibition of T cell differentiation. J Exp Med. 2003 Jun 16;197(12):1689-99.

Chou J, Burke NA, Iwabu A, Watkins SC, Wells A. Directional motility induced by epidermal growth factor requires Cdc42.Exp Cell Res. 2003 Jul 1;287(1):47-56.

Hughes DE, Stolz DB, Yu S, Tan Y, Reddy JK, Watkins SC, Diehl AM, Costa RH. Elevated hepatocyte levels of the Forkhead box A2 (HNF-3beta) transcriptionfactor cause postnatal steatosis and mitochondrial damage. Hepatology. 2003 Jun;37(6):1414-24.

Yang R, Han X, Uchiyama T, Watkins SK, Yaguchi A, Delude RL, Fink MP. IL-6 is essential for the development of gut barrier dysfunction after hemorrhagic shock and resuscitation in mice.Am J Physiol Gastrointest Liver Physiol. 2003 May 28

Wang X, Ryter SW, Dai C, Tang ZL, Watkins SC, Yin XM, Song R, Choi AM. Necrotic cell death in response to oxidant stress involves the activation of the apoptogenic caspase-8/Bid pathway.J Biol Chem. 2003 May 15

Zhang X, Graham SH, Kochanek PM, Marion DW, Nathaniel PD, Watkins SC, Clark RS. Caspase-8 expression and proteolysis in human brain after severe head injury. FASEB J. 2003 Jul;17(10):1367-9. Epub 2003 May 08.

Lawler C, Suk WA, Pitt BR, Croix CM, Watkins SC. Multimodal optical imaging.Am J Physiol Lung Cell Mol Physiol. 2003 Aug;285(2):L269-80

Mi Z, Lu X, Mai JC, Ng BG, Wang G, Lechman ER, Watkins SC, Rabinowich H,Robbins PD. Identification of a synovial fibroblast-specific protein transduction domainfor delivery of apoptotic agents to hyperplastic synovium.Mol Ther. 2003 Aug;8(2):295-305.

Pathre P. Shome K. Blumental-Perry A. Bielli A. Haney CJ. Alber S. Watkins SC. Romero G. Aridor M. Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export. EMBO Journal. 22(16):4059-69, 2003 August 15.

Hong KU, Reynolds SD, Watkins S, Fuchs E, Stripp BR. In vivo differentiation potential of tracheal basal cells: Evidence for multipotent and unipotent subpopulations.Am J Physiol Lung Cell Mol Physiol. 2003

Zhao Y, Ding WX, Qian T, Watkins S, Lemasters JJ, Yin XM. Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement. Gastroenterology. 2003 Sep;125(3):854-67.

Tatsumi T, Huang J, Gooding WE, Gambotto A, Robbins PD, Vujanovic NL, AlberSM, Watkins SC, Okada H, Storkus WJ. Intratumoral Delivery of Dendritic Cells Engineered to Secrete Both Interleukin (IL)-12 and IL-18 Effectively Treats Local and Distant Disease in Association with Broadly Reactive Tc1-type Immunity.Cancer Res. 2003 Oct 1;63(19):6378-6386. 2: (COVER)

Phadke SM, Islam K, Deslouches B, Kapoor SA, Beer Stolz D, Watkins SC, Montelaro RC, Pilewski JM, Mietzner TA. Selective toxicity of engineered lentivirus lytic peptides in a CF airway cell model Peptides. 2003 Aug;24(8):1099-107.

Kuddus RH, Gandhi CR, Rehman KK, Guo F, Watkins SC, Valdivia LA, Fung JJ. Some morphological, growth, and genomic properties of human cells chronically infected with porcine endogenous retrovirus (PERV). Genome. 2003 Oct;46(5):858-69.

Bertera S, Geng X, Tawadrous Z, Bottino R, Balamurugan AN, Rudert WA, Drain P, Watkins SC, Trucco M. Body window-enabled in vivo multicolor imaging of transplanted mouse islets expressing an insulin-Timer fusion protein. Biotechniques. 2003 Oct;35(4):718-22. (COVER)

Brown K, Gao W, Alber S, Trichel A, Murphey-Corb M, Watkins SC, Gambotto A,Barratt-Boyes SM. Adenovirus-transduced dendritic cells injected into skin or lymph node prime potent simian immunodeficiency virus-specific T cell immunity in monkeys. J Immunol. 2003 Dec 15;171(12):6875-82.

Zhu JH, Guo F, Shelburne J, Watkins S, Chu CT. Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases. Brain Pathol. 2003 Oct;13(4):473-81.

Znati CA, Rosenstein M, McKee TD, Brown E, Turner D, Bloomer WD, Watkins S, Jain RK, Boucher Y. Irradiation reduces interstitial fluid transport and increases the collagen content in tumors.Clin Cancer Res. 2003 Nov 15;9(15):5508-13.

Bergman I, Whitaker-Dowling P, Gao Y, Griffin JA, Watkins SC. Vesicular stomatitis virus expressing a chimeric Sindbis glycoprotein containing an Fc antibody binding domain targets to Her2/neu overexpressing breast cancer cells. Virology. 2003 Nov 25;316(2):337-47.

Steinman R, Yaroslavskiy B, Goff JP, Alber SM, Watkins SC. Cdk-inhibitors and exit from quiescence in primitive haematopoietic cell subsets. Br J Haematol. 2004 Feb;124(3):358-65.

Chen C, Weisz OA, Stolz DB, Watkins SC, Montelaro RC. Differential effects of actin cytoskeleton dynamics on equine infectious anemia virus particle production. J Virol. 2004 Jan;78(2):882-91.

Brown K, Gao W, Alber S, Trichel A, Murphey-Corb M, Watkins SC, Gambotto A, Barratt-Boyes SM. Adenovirus-transduced dendritic cells injected into skin or lymph node prime potent simian immunodeficiency virus-specific T cell immunity in monkeys. J Immunol. 2003 Dec 15;171(12):6875-82.

JH, Guo F, Shelburne J, Watkins S, Chu CT. Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases. Brain Pathol. 2003 Oct;13(4):473-81.

Salter RD, Tuma-Warrino RJ, Hu PQ, Watkins SC. Rapid and extensive membrane reorganization by dendritic cells following exposure to bacteria revealed by high-resolution imaging. J Leukoc Biol. 2004 Feb;75(2):240-3.(COVER)

Wang Z, Cook T, Alber S, Liu K, Kovesdi I, Watkins SC, Vodovotz Y, Billiar TR, Blumberg D. Adenoviral gene transfer of the human inducible nitric oxide synthase gene enhances the radiation response of human colorectal cancer associated with alterations in tumor vascularity. Cancer Res. 2004 Feb 15;64(4):1386-95.

Jones HM, Hamilton KL, Papworth GD, Syme CA, Watkins SC, Bradbury NA, Devor DC. Role of the NH2-terminus in the assembly and trafficking of the intermediate conductance Ca2+-activated K+ channel, hIK1.J Biol Chem. 2004 Jan 30

Hong KU, Reynolds SD, Watkins S, Fuchs E, Stripp BR. Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol. 2004 Feb;164(2):577-88.

Larregina AT, Morelli AE, Tkacheva O, Erdos G, Donahue C, Watkins SC,Thomson AW, Falo LD Jr. Highly efficient expression of transgenic proteins by naked DNA-transfected dendritic cells through terminal differentiation.Blood. 2004 Feb 1;103(3):811-9

Hu PQ, Tuma-Warrino RJ, Bryan MA, Mitchell KG, Higgins DE, Watkins SC ,Salter RD. Escherichia coli expressing recombinant antigen and listeriolysin O stimulate class I-restricted CD8+ T cells following uptake by human APC.J Immunol. 2004 Feb 1;172(3):1595-601

Keyel PA, Watkins SC, Traub LM. Endocytic adaptor molecules reveal an endosomal population of clathrin by total internal reflection fluorescence microscopy.J Biol Chem. 2004 Jan 12

Moalli PA, Talarico LC, Sung VW, Klingensmith WL, Shand SH, Meyn LA, Watkins SC. Impact of menopause on collagen subtypes in the arcus tendineous fasciae pelvis.Am J Obstet Gynecol. 2004 Mar;190(3):620-7.

Hoffelder DR , Luo L, Burke NA, Watkins SC, Gollin SM, Saunders WS. Resolution of anaphase bridges in cancer cells. Chromosoma. 2004 Jun;112(8):389-97.

Yang R, Uchiyama T, Alber SM, Han X, Watkins SK, Delude RL, Fink MP. Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis. Crit Care Med. 2004 Jul;32(7):1453-9.

Du L, Bayir H, Lai Y, Zhang X, Kochanek PM, Watkins SC, Graham SH, Clark RS. Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway. J Biol Chem. 2004 Jul 1

Baker LC, Wolk R, Choi BR, Watkins S, Plan P, Shah A, Salama G. Effects of Mechanical uncouplers, Diacetyl Monoxime and Cytochalasin-D on the Electrophysiology of Perfused Mouse Hearts. Am J Physiol Heart Circ Physiol. 2004 Jun 10

Tsugawa T, Kuwashima N, Sato H, Fellows-Mayle WK, Dusak JE, Okada K, Papworth GD, Watkins SC, Gambotto A, Yoshida J, Pollack IF, Okada H. Sequential delivery of interferon-alpha gene and DCs to intracranial gliomas promotes an effective antitumor response.Gene Ther. 2004 Sep 2

Mizuno Y, Guyon JR, Watkins SC, Mizushima K, Sasaoka T, Imamura M, Kunkel LM, Okamoto K Beta-synemin localizes to regions of high stress in human skeletal myofibers. Muscle Nerve. 2004 Sep;30(3):337-46.

Ramani R, Mathier M, Wang P, Gibson G, Togel S, Dawson J, Bauer A, Alber S, Watkins SC, McTiernan CF, Feldman AM. Inhibition of tumor necrosis factor receptor-1-mediated pathways has beneficial effects in a murine model of postischemic remodeling.Am J Physiol Heart Circ Physiol. 2004 Sep;287(3):H1369-77

Okada H, Tsugawa T, Sato H, Kuwashima N, Gambotto A, Okada K, Dusak JE, Fellows-Mayle WK, Papworth GD, Watkins SC, Chambers WH, Potter DM, Storkus WJ, Pollack IF. Delivery of interferon-alpha transfected dendritic cells into central nervous system tumors enhances the antitumor efficacy of peripheral peptide-based vaccines.Cancer Res. 2004 Aug 15;64(16):5830-8.

St Croix CM, Stitt MS, Leelavanichkul K, Wasserloos KJ, Pitt BR, Watkins SC. Nitric oxide-induced modification of protein thiolate clusters as determined by spectral fluorescence resonance energy transfer in live endothelial cells. Free Radic Biol Med. 2004 Sep 15;37(6):785-92.

Cetin S, Dunklebarger J, Li J, Boyle P, Ergun O, Qureshi F, Ford H, Upperman J, Watkins S, Hackam DJ. Endotoxin differentially modulates the basolateral and apical sodium/proton exchangers (NHE) in enterocytes. Surgery. 2004 Aug;136(2):375-83.

Tan RJ, Fattman CL, Watkins SC, Oury TD. Redistribution of pulmonary EC-SOD after exposure to asbestos.J Appl Physiol. 2004 Aug 6

Morelli AE, Larregina AT, Shufesky WJ, Sullivan ML, Stolz DB, Papworth GD, Zahorchak AF, Logar AJ, Wang Z, Watkins SC, Falo Jr LD, Thomson AW. Endocytosis, Intracellular Sorting and Processing of Exosomes by Dendritic Cells. Blood. 2004 Jul 29

Ho M, Post CM, Donahue LR, Lidov HG, Bronson RT, Goolsby H, Watkins SC, Cox GA, Brown RH Jr. Disruption of muscle membrane and phenotype divergence in two novel mouse models of dysferlin deficiency. Hum Mol Genet. 2004 Sep 15;13(18):1999-2010

Thotala D, Schafer EA, Majumder B, Janket ML, Wagner M, Srinivasan A,Watkins S, Ayyavoo V. Structure-functional analysis of human immunodeficiency virus type 1 (HIV-1)Vpr: role of leucine residues on Vpr-mediated transactivation and virus replicat ion.Virology. 2004 Oct 15;328(1):89-100.

Yang R, Uchiyama T, Watkins SC, Han X, Fink MP. Ethyl pyruvate reduces liver injury in a murine model of extrahepatic cholestasis.shock. 2004 oct;22(4):369-375.

Zhu Y, Stolz DB, Guo F, Ross MA, Watkins SC, Tan BJ, Qi RZ, Manser E, Li QT,Bay BH, Teo TS, Duan W. Signaling via a novel integral plasma membrane pool of a serine/threonine protein kinase PRK1 in mammalian cells.FASEB J. 2004 Sep 16

Cook T, Wang Z, Alber S, Liu K, Watkins SC, Vodovotz Y, Billiar TR, Blumberg D. Nitric Oxide and Ionizing Radiation Synergistically Promote Apoptosis and Growth Inhibition of Cancer by Activating p53.Cancer Res. 2004 Nov 1;64(21):8015-21.

Bertera S, Alexander AM, Crawford ML, Papworth G, Watkins SC, Robbins PD,Trucco M. Gene combination transfer to block autoimmune damage in transplanted islets of Langerhans. Exp Diabesity Res. 2004 Jul-Sep;5(3):201-10. (COVER)

Ning W, Li CJ, Kaminski N, Feghali-Bostwick CA, Alber SM, Di YP, Otterbein SL, Song R, Hayashi S, Zhou Z, Pinsky DJ, Watkins SC, Pilewski JM, Sciurba FC, Peters DG, Hogg JC, Choi AM. Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease.Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14895-900. Epub 2004 Oct 05.

Kawaguchi Y, McCarthy SA, Watkins SC, Wright TM. Autocrine activation by interleukin 1alpha induces the fibrogenic phenotype of systemic sclerosis fibroblasts. J Rheumatol. 2004 Oct;31(10):1946-54.

Thirunavukkarasu C, Watkins S, Harvey SA, Gandhi CR. Superoxide-induced apoptosis of activated rat hepatic stellate cells. J Hepatol. 2004 Oct;41(4):567-75.

Chen Y, Helmus R, McClane B, Hoffman R, Watkins S, Wehrli T, Gupt a P. Use of a Clostridium perfringens vector to express high levels of SIV p2 protein for the development of an oral SIV vaccine. Virology. 2004 Nov 24;329(2):226-33.

Cook T, Wang Z, Alber S, Liu K, Watkins SC, Vodovotz Y, Billiar TR, Blumberg D. Nitric oxide and ionizing radiation synergistically promote apoptosis and growth inhibition of cancer by activating p53. Cancer Res. 2004 Nov 1;64(21):8015-21.

Pizzoferrato E, Liu Y, Gambotto A, Armstrong MJ, Stang MT, Gooding WE, AlberSM, Shand SH, Watkins SC, Storkus WJ, Yim JH. Ectopic expression of interferon regulatory factor-1 promotes human breastcancer cell death and results in reduced expression of survivin.Cancer Res. 2004 Nov 15;64(22):8381-8

Makarenkova V, Chakrabarti AK, Liberatore JA, Popovic P, Lu G, Watkins S,Vujanovic NL. Dendritic cells and natural killer cells interact via multiple TNF familymolecules. J Leukoc Biol. 2004 Dec 16

Mahidhara RS, Queiroz De Oliveira PE, Kohout J, Beer DG, Lin J, Watkins SC,Robbins PD, Hughes SJ. Altered trafficking of Fas and subsequent resistance to Fas-mediated apoptosis occurs by a wild-type p53 independent mechanism in esophageal adenocarcinoma(1).J Surg Res. 2005 Feb;123(2):302-11.

Gkretsi V, Zhang Y, Tu Y, Chen K, Stolz DB, Yang Y, Watkins SC, Wu C. Physical and functional association of migfilin with cell-cell adhesions.J Cell Sci. 2005 Feb 15;118(Pt 4):697-710. Epub 2005 Jan 25.

Oriss TB, Ostroukhova M, Seguin-Devaux C, Dixon-McCarthy B, Stolz DB,Watkins SC, Pillemer B, Ray P, Ray A. Dynamics of dendritic cell phenotype and interactions with CD4+ T cells in airway inflammation and tolerance. J Immunol. 2005 Jan 15;174(2):854-63.

Weixel KM, Blumental-Perry A, Watkins SC, Aridor M, Weisz OA. Distinct golgi populations of phophatidylinositol 4-phosphate regulated by phosphatidylinositol 4-kinases.J Biol Chem. 2005 Jan 5;

Kim SH, Lechman ER, Bianco N, Menon R, Keravala A, Nash J, Mi Z, Watkins SC, Gambotto A, Robbins PD. Exosomes Derived from IL-10-Treated Dendritic Cells Can Suppress Inflammation and Collagen-Induced Arthritis.J Immunol. 2005 May 15;174(10):6440-8.

Sato H, Kuwashima N, Sakaida T, Hatano M, Dusak JE, Fellows-Mayle WK, Papworth GD, Watkins SC, Gambotto A, Pollack IF, Okada H. Epidermal growth factor receptor-transfected bone marrow stromal cells exhibit enhanced migratory response and therapeutic potential against murine brain tumors. Cancer Gene Ther. 2005 Apr 15;

Qureshi FG, Leaphart C, Cetin S, Li J, Grishin A, Watkins S, Ford HR, Hackam DJ. Increased expression and function of integrins I enterocytes by endotoxin impairs epithelial restitution. Gastroenterology. 2005 Apr;128(4):1012-22.

Kane LP, Watkins SC. Dynamic regulation of Tec kinase localization in membrane-proximal vesicles of a T cell clone revealed by TIRF and confocal microscopy. J Biol Chem. 2005 Apr 6

Witham TF, Okada H, Fellows W, Hamilton RL, Flickinger JC, Chambers WH, Pollack IF, Watkins SC, Kondziolka D. The Characterization of Tumor Apoptosis after Experimental Radiosurgery. Stereotact Funct Neurosurg. 2005 Mar 15;83(1):17-24

Singh SV, Srivastava SK, Choi S, Lew KL, Antosiewicz J, Xiao D, Zeng Y, Watkins SC, Johnson CS, Trump DL, Lee YJ, Xiao H, Herman-Antosiewicz A. Sulforaphane-induced Cell Death in Human Prostate Cancer Cells Is Initiated by Reactive Oxygen Species. J Biol Chem. 2005 May 20;280(20):19911-24.

Kim JW, Wieckowski E, Taylor DD, Reichert TE, Watkins S, Whiteside TL. Fas ligand-positive membranous vesicles isolated from sera of patients with oral cancer induce apoptosis of activated T lymphocytes. Clin Cancer Res. 2005 Feb 1;11(3):1010-20.

Wilson A, Zhou W, Champion HC, Alber S, Tang ZL, Kennel S, Watkins S, Huang , Pitt B, Li S. Targeted Delivery of Oligodeoxynucleotides to Mouse Lung Endothelial Cells in Vitro and in Vivo. Mol Ther. 2005 Jun 10;

Evans CH, Robbins PD, Ghivizzani SC, Wasko MC, Tomaino MM, Kang R, Muzzonigro TA, Vogt M, Elder EM, Whiteside TL, Watkins SC, Herndon JH. Gene transfer to human joints: progress toward a gene therapy of arthritis. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8698-703.

Kuwashima N, Nishimura F, Eguchi J, Sato H, Hatano M, Tsugawa T, Sakaida T,Dusak JE, Fellows-Mayle WK, Papworth GD, Watkins SC, Gambotto A, Pollack IF, Storkus WJ, Okada H. Delivery of Dendritic Cells Engineered to Secrete IFN-{alpha} into Central Nervous System Tumors Enhances the Efficacy of Peripheral Tumor Cell Vaccines:Dependence on Apoptotic Pathways. J. Immunol. 2005 Aug 15;175(4):2730-40.

Engelmayr GC Jr, Papworth GD, Watkins SC, Mayer JE Jr, Sacks MS. Guidance of engineered tissue collagen orientation by large-scale scaffold microstructures. J Biomech. 2005 Jul 23;

Weis BK, Balshaw D, Barr JR, Brown D, Ellisman M, Lioy P, Omenn G, Potter JD, Smith MT, Sohn L, Suk WA, Sumner S, Swenberg J, Walt DR, Watkins S, Thompson C, Wilson SH. Personalized exposure assessment: promising approaches for human environmental health research. Environ Health Perspect. 2005 Jul;113(7):840-8.

Thirunavukkarasu C, Uemura T, Wang LF, Watkins SC, Gandhi CR. Normal rat hepatic stellate cells respond to endotoxin in LBP-independent manner to produce inhibitor(s) of DNA synthesis in hepatocytes. J Cell Physiol. 2005 Aug;204(2):654-65

Hokey DA, Larregina AT, Erdos G, Watkins SC, Falo LD Jr. Tumor cell loaded type-1 polarized dendritic cells induce Th1-mediated tumor immunity.Cancer Res. 2005 Nov 1;65(21):10059-67.

Kim JH, Majumder N, Lin H, Watkins S, Falo LD, You Z. Induction of therapeutic antitumor immunity by in vivo administration of a lentiviral vaccine. Hum Gene Ther. 2005 Nov;16(11):1255-66.

Hennegan K, Yang D, Nguyen D, Wu L, Goding J, Huang J, Guo F, Huang N, Watkins SC. Improvement of Human lysozyme Expression in Transgenic Rice Grain by Combining Wheat (Triticum aestivum) puroindoline b and Rice (Oryza sativa) Gt1 Promotersand Signal Peptides. Transgenic Res. 2005 Oct;14(5):583-92.

St Croix CM, Leelavaninchkul K, Watkins SC, Kagan VE, Pitt BR. Nitric oxide and zinc homeostasis in acute lung injury. Proc Am Thorac Soc. 2005;2(3):236-42.

Mailliard RB, Alber SM, Shen H, Watkins SC, Kirkwood JM, Herberman RB,Kalinski P. IL-18-induced CD83+CCR7+ NK helper cells. J Exp Med. 2005 Oct 3;202(7):941-53.

Loughran PA, Stolz DB, Vodovotz Y, Watkins SC, Simmons RL, Billiar TR. Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes. Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13837-42. Epub 2005 Sep 19.

Rogulski K, Li Y, Rothermund K, Pu L, Watkins S, Yi F, Prochownik EV. Onzin, a c-Myc-repressed target, promotes survival and transformation by modulating the Akt-Mdm2-p53 pathway. Oncogene. 2005 Sep 19; St. Croix , C.M., Pitt, B.R. and Watkins, S.C. The use of contemporary fluorescent imaging technologies in biomedical research. Medicine and Science. 10 (1): 16-29, 2005.

Watkins SC, Salter RD. Functional connectivity between immune cells mediated by tunneling nanotubules. Immunity. 2005 Sep;23(3):309-18.

Huang X, Raskovalova T, Lokshin A, Krasinskas A, Devlin J, Watkins S, Wolf SF, Gorelik E. Combined antiangiogenic and immune therapy of prostate cancer. Angiogenesis. 2005;8(1):13-23.

Qiao C, Li J, Zhu T, Draviam R, Watkins S, Ye X, Chen C, Li J, Xiao X. Amelioration of laminin-alpha2-deficient congenital muscular dystrophy by somatic gene transfer of miniagrin. Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):11999

St. Croix, C.M., Shand, S. and Watkins, S.C. Confocal microscopy; comparisons, applications and problems. Biotechniques 39: S2-S5, 2005.

He F, Li J, Mu Y, Kuruba R, Ma Z, Wilson A, Alber S, Jiang Y, Stevens T,Watkins S, Pitt B, Xie W, Li S. Downregulation of Endothelin-1 by Farnesoid X Receptor in Vascular Endothelial Cells. Circ Res. 2005 Dec 15;

Bielli A, Haney CJ, Gabreski G, Watkins SC, Bannykh SI, Aridor M. Regulation of Sar1 NH2 terminus by GTP binding and hydrolysis promotes membrane deformation to control COPII vesicle fission.J Cell Biol. 2005 Dec 12

St Croix CM, Stitt MS, Watkins SC, Pitt BR. Fluorescence resonance energy transfer-based assays for the real-time detection of nitric oxide signaling. Methods Enzymol. 2005;396:317-26.

Rappocciolo G, Jenkins FJ, Hensler HR, Piazza P, Jais M, Borowski L, Watkins SC, Rinaldo CR Jr. DC-SIGN Is a Receptor for Human Herpesvirus 8 on Dendritic Cells and Macrophages. J Immunol. 2006 Feb 1;176(3):1741-9.